BDBM510814 N-(2-(1H-Indol-3-yl)ethyl)-2-(4- methylpiperazin-1-yl)thiazole-5- carboxamide::US11078196, Ex. 2

SMILES CN1CCN(CC1)c1ncc(s1)C(=O)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=CVPVFXOHGCRRAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510814   

TargetAlpha-synuclein(Human)
Ucb Biophama

US Patent
LigandPNGBDBM510814(N-(2-(1H-Indol-3-yl)ethyl)-2-(4- methylpiperazin-1...)
Affinity DataIC50: 3.55E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent