BDBM510816 N-(2-(1H-Indol-3-yl)ethyl)-2-(2- (4-methylpiperazin-1- yl)ethyl)thiazole-5-carboxamide::US11078196, Ex. 4

SMILES CN1CCN(CCc2ncc(s2)C(=O)NCCc2c[nH]c3ccccc23)CC1

InChI Key InChIKey=YULQAYQMPLAAAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510816   

TargetAlpha-synuclein(Human)
Ucb Biophama

US Patent
LigandPNGBDBM510816(N-(2-(1H-Indol-3-yl)ethyl)-2-(2- (4-methylpiperazi...)
Affinity DataIC50: 5.90E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent