BDBM510819 N-(1-(1H-Indol-3-yl)hexan-2- yl)-5-(4-methylpiperazin-1-yl)- 1,3,4-thiadiazole-2-carboxamide::US11078196, Ex. 7

SMILES CCCCC(Cc1c[nH]c2ccccc12)NC(=O)c1nnc(o1)N1CCN(C)CC1

InChI Key InChIKey=XKJMFCLYPUAGMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510819   

TargetAlpha-synuclein(Human)
Ucb Biophama

US Patent
LigandPNGBDBM510819(N-(1-(1H-Indol-3-yl)hexan-2- yl)-5-(4-methylpipera...)
Affinity DataIC50: 370nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent