BDBM511657 US11059801, Compound D-24

SMILES Fc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1

InChI Key InChIKey=MPQLCQKBYRSPNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 511657   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM511657(US11059801, Compound D-24 | US20250313547, Example...)
Affinity DataIC50: 493nMAssay Description:A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetProtein cereblon(Human)
Arvinas Operations

US Patent
LigandPNGBDBM511657(US11059801, Compound D-24 | US20250313547, Example...)
Affinity DataKd: >1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2026
Entry Details US Patent

TargetProtein cereblon(Human)
Arvinas Operations

US Patent
LigandPNGBDBM511657(US11059801, Compound D-24 | US20250313547, Example...)
Affinity DataKd: >1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent