BDBM513668 US11091495, Example 29::US11220509, Example 29::US11485738, Example 29

SMILES Cc1cc(-c2cnc(NCc3c4CCOc4ccc3Cl)n3cc(nc23)C#N)n(C)n1

InChI Key InChIKey=NLRGHQHTQSTZQE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 513668   

LigandChemical structure of BindingDB Monomer ID 513668BDBM513668(US11220509, Example 29 | US11091495, Example 29 | ...)
Affinity DataIC50: 500nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513668BDBM513668(US11220509, Example 29 | US11091495, Example 29 | ...)
Affinity DataIC50: 500nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513668BDBM513668(US11220509, Example 29 | US11091495, Example 29 | ...)
Affinity DataIC50: 500nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513668BDBM513668(US11220509, Example 29 | US11091495, Example 29 | ...)
Affinity DataIC50: 500nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent