BDBM513743 US11091495, Example 104::US11220509, Example 104::US11485738, Example 104

SMILES Cc1n[nH]c(C)c1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cc(C#N)nc12

InChI Key InChIKey=NCSVBCQCTXBRFJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 513743   

LigandChemical structure of BindingDB Monomer ID 513743BDBM513743(US11220509, Example 104 | US11091495, Example 104 ...)
Affinity DataIC50: 500nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513743BDBM513743(US11220509, Example 104 | US11091495, Example 104 ...)
Affinity DataIC50: 500nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513743BDBM513743(US11220509, Example 104 | US11091495, Example 104 ...)
Affinity DataIC50: 500nMAssay Description:Briefly, compounds of the present disclosure were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513743BDBM513743(US11220509, Example 104 | US11091495, Example 104 ...)
Affinity DataIC50: 500nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent