BDBM513792 5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-8-(1-((tetrahydrofuran-2-yl)methyl)-1H-pyrazol-3-yl)imidazo[1,2-c]pyrimidine-2-carbonitrile::US11091495, Example 153::US20240398811, Example 153

SMILES Fc1ccc2OCCc2c1CNc1ncc(-c2ccn(CC3CCCO3)n2)c2nc(cn12)C#N

InChI Key InChIKey=PIRZDXQMMZIWOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513792   

LigandChemical structure of BindingDB Monomer ID 513792BDBM513792(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present disclosure were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513792BDBM513792(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent