BDBM513842 5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-8-(1,2,3,4-tetrahydroisoquinolin-6-yl)imidazo[1,2-c]pyrimidine-2-carbonitrile::US11091495, Example 203::US11220509, Example 203::US11485738, Example 203

SMILES Fc1ccc2OCCc2c1CNc1ncc(-c2ccc3CNCCc3c2)c2nc(cn12)C#N

InChI Key InChIKey=WVAWYXLXRBQNHE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 513842   

LigandChemical structure of BindingDB Monomer ID 513842BDBM513842(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 300nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513842BDBM513842(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513842BDBM513842(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513842BDBM513842(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513842BDBM513842(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent