BDBM513851 5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-8-(2-methyl-4-(pyrrolidin-2-yl)phenyl)imidazo[1,2-c]pyrimidine-2-carbonitrile::US11091495, Example 213::US11485738, Example 213

SMILES Cc1cc(ccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cc(nc12)C#N)[C@@H]1CCCN1

InChI Key InChIKey=QKETUAWXXUWCHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513851   

LigandPNGBDBM513851(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandPNGBDBM513851(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 100nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent