BDBM513867 5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-8-(1-methyl-3-(4-methylpiperazine-1-carbonyl)-1H-pyrazol-5-yl)imidazo[1,2-c]pyrimidine-2-carbonitrile::US11091495, Example 229::US11220509, Example 229::US11485738, Example 229

SMILES CN1CCN(CC1)C(=O)c1cc(-c2cnc(NCc3c4CCOc4ccc3F)n3cc(nc23)C#N)n(C)n1

InChI Key InChIKey=JTCGIKFKCGLAPJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 513867   

LigandPNGBDBM513867(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM513867(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM513867(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM513867(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandPNGBDBM513867(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)am...)
Affinity DataIC50: 100nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent