BDBM51645 6-(4-methoxyphenyl)-1H-thieno[3,2-d]pyrimidin-4-one::6-(4-methoxyphenyl)thieno[3,2-d]pyrimidin-4(3H)-one::CHEMBL1612732::MLS000530458::SMR000135436::cid_754900

SMILES COc1ccc(cc1)-c1cc2nc[nH]c(=O)c2s1

InChI Key InChIKey=YLBLDEDUUJNEOU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 51645   

TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM51645(MLS000530458 | cid_754900 | 6-(4-methoxyphenyl)thi...)
Affinity DataIC50: 5.66E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Michael McNeil, Colorado State Universi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2011
Entry Details
PCBioAssay
LigandPNGBDBM51645(MLS000530458 | cid_754900 | 6-(4-methoxyphenyl)thi...)
Affinity DataIC50: 8.60E+4nMAssay Description:Competitive inhibition of PDK1 using [gamma-33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM51645(MLS000530458 | cid_754900 | 6-(4-methoxyphenyl)thi...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay