BDBM517136 5-(cyclohexylmethyl)-6-methyl-1- propyl-pyrazolo[3,4-d]pyrimidin-4- one::US11104680, Example 5

SMILES CCCn1ncc2c1nc(C)n(CC1CCCCC1)c2=O

InChI Key InChIKey=TYMBPQQASYCWEH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 517136   

LigandPNGBDBM517136(US11104680, Example 5 | 5-(cyclohexylmethyl)-6-met...)
Affinity DataIC50: 31nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517136(US11104680, Example 5 | 5-(cyclohexylmethyl)-6-met...)
Affinity DataIC50: 36nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517136(US11104680, Example 5 | 5-(cyclohexylmethyl)-6-met...)
Affinity DataIC50: 111nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent