BDBM517148 5-(1,3-benzodioxol-5-ylmethyl)-6- methyl-1-tetrahydropyran-4-yl- pyrazolo[4,3-c]pyridin-4-one::US11104680, Example 17

SMILES Cc1cc2n(ncc2c(=O)n1Cc1ccc2OCOc2c1)C1CCOCC1

InChI Key InChIKey=APQLMNUUGPWXRZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 517148   

LigandPNGBDBM517148(US11104680, Example 17 | 5-(1,3-benzodioxol-5-ylme...)
Affinity DataIC50: 154nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517148(US11104680, Example 17 | 5-(1,3-benzodioxol-5-ylme...)
Affinity DataIC50: 429nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517148(US11104680, Example 17 | 5-(1,3-benzodioxol-5-ylme...)
Affinity DataIC50: 662nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent