BDBM518018 2-[4-[[4-(2R)-3-(3,4,-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propyl]-5-oxo-2,3,-dihydro- 1,4,-benzoxazepin-8-yl]-1-piperidyl]acetonitrile::US11111237, Example 159::US11725001, Example 159

SMILES O[C@H](CN1CCc2ccccc2C1)CN1CCOc2cc(OC3CCN(CC#N)CC3)ccc2C1=O

InChI Key InChIKey=UEMHJPQQUMDYOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518018   

TargetProtein arginine N-methyltransferase 5(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 518018BDBM518018(US11111237, Example 159 | 2-[4-[[4-(2R)-3-(3,4,-di...)
Affinity DataIC50: 550nMAssay Description:Experimental procedure: The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 518018BDBM518018(US11111237, Example 159 | 2-[4-[[4-(2R)-3-(3,4,-di...)
Affinity DataIC50: 550nMAssay Description:The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto the plate per 100 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2023
Entry Details
US Patent