BDBM518030 4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propyl]-2,2-dimethyl-8-(2-oxa-6- azaspiro[3.3]heptan-6-ylmethyl)-3H-1,4-benzoxazepin-5-one::US11111237, Example 170::US11725001, Example 170

SMILES CC1(C)CN(C[C@H](O)CN2CCc3ccccc3C2)C(=O)c2ccc(CN3CC4(COC4)C3)cc2O1

InChI Key InChIKey=UQNDCGWZEZJRLX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518030   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 518030BDBM518030(US11111237, Example 170 | 4-[(2R)-3-(3,4-dihydro-1...)
Affinity DataIC50: 550nMAssay Description:The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto the plate per 100 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2023
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 518030BDBM518030(US11111237, Example 170 | 4-[(2R)-3-(3,4-dihydro-1...)
Affinity DataIC50: 550nMAssay Description:Experimental procedure: The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent