BDBM518735 N6-(5-chloro-1- ((3S,4S)-3- fluoro-1-(oxetan- 3-yl)piperidin-4- yl)-1H -pyrazol-4- yl)-N4-ethyl-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]pyridine-4,6- diamine::US11117892, Example 69
SMILES CCNc1cc(Nc2cnn([C@H]3CCN(C[C@@H]3F)C3COC3)c2Cl)nc2[nH]cc(c12)C(F)(F)F
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 518735
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 55nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair