BDBM518760 N6-(5-chloro-1- ((3S,4S)-3- fluoro-1-(oxetan- 3-yl)piperidin-4- yl)-1H-pyrazol-4- yl)-3- methoxyethyl)-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]pyridine-4,6- diamine::US11117892, Example 79

SMILES COCCNc1cc(Nc2cnn([C@H]3CCN(C[C@@H]3F)C3COC3)c2Cl)nc2[nH]cc(c12)C(F)(F)F

InChI Key InChIKey=QCJSRMGFDHRSCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518760   

LigandPNGBDBM518760(US11117892, Example 79 | N6-(5-chloro-1- ((3S,4S)-...)
Affinity DataIC50: 55nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair
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Date in BDB:
2/26/2022
Entry Details
US Patent