BDBM518775 (R)-(4-((4-((1- hydroxy-3- methylbutan-2-yl) amino)-3- (trifluoromethyl)- 1H-pyrrolo[2,3- b]amino)-3- methoxyphenyl) (4-morpholino- piperidin-1-yl) methanone::US11117892, Example 91

SMILES COc1cc(ccc1Nc1cc(N[C@@H](CO)C(C)C)c2c(c[nH]c2n1)C(F)(F)F)C(=O)N1CCC(CC1)N1CCOCC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518775   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM518775((R)-(4-((4-((1- hydroxy-3- methylbutan-2-yl) amino...)
Affinity DataIC50:  55nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent