BDBM518904 US11116757, No. A199::US11116757, No. A200

SMILES CCC(=O)Nc1ccccc1CN(C1CCN(CCCC#C)CC1)C(=O)Nc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PHWNHGSSGNBMPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518904   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
Memorial Sloan Kettering Cancer Center

US Patent
LigandChemical structure of BindingDB Monomer ID 518904BDBM518904(US11116757, No. A200 | US11116757, No. A199)
Affinity DataIC50: 1.45E+4nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
Memorial Sloan Kettering Cancer Center

US Patent
LigandChemical structure of BindingDB Monomer ID 518904BDBM518904(US11116757, No. A200 | US11116757, No. A199)
Affinity DataIC50: 1.50E+4nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent