BDBM519472 US11142505, FAH #48::US20210101879, Compound FAH-48

SMILES COc1cc(ccn1)C1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)c(C)c1

InChI Key InChIKey=XVIKZENOIXNJIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 519472   

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519472BDBM519472(US11142505, FAH #48 | US20210101879, Compound FAH-...)
Affinity DataIC50: 4.80E+3nMAssay Description:Approximately 200 nM to 10 μM substrate, approximately 10 to 200 pM enzyme, and approximately 0.1 nM to 10 μM of the agent(s), in aqueous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519472BDBM519472(US11142505, FAH #48 | US20210101879, Compound FAH-...)
Affinity DataIC50: 4.80E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent