BDBM519628 2-((6-cyano-7-methyl-3H-imidazo[4,5-::US11142524, Compound 109

SMILES COc1ccc(NC(=O)CSc2nc3c(C)c(ncc3[nH]2)C#N)cc1OCCO

InChI Key InChIKey=UHAPAXUIZIIZCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 519628   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Stingray Therapeutics

US Patent
LigandPNGBDBM519628(2-((6-cyano-7-methyl-3H-imidazo[4,5- | US11142524,...)
Affinity DataIC50: 3.26E+3nMAssay Description:MaterialsAssay Buffer: 1 mM CaCl2, 0.2 mM ZnCl2, 50 mM Tris, pH 9.0. Substrate: 100 μM Adenosine 5′-triphosphate disodium salt hydrate (Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Stingray Therapeutics

US Patent
LigandPNGBDBM519628(2-((6-cyano-7-methyl-3H-imidazo[4,5- | US11142524,...)
Affinity DataIC50: 3.61E+3nMAssay Description:Materials:Assay Buffer: 1 mM CaCl2, 0.2 mM ZnCl2, 50 mM Tris, pH 9.0 Substrate: 1.5 mM Thymidine 5′-monophosphate disodium salt hydrate (Sigma:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent