BDBM519649 US11142525, Example 50

SMILES CNCc1nc(N)cc2C(=O)N(Cc12)c1cccc(n1)-c1nncn1C(C)C

InChI Key InChIKey=RPAAUIAPPXJLJR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519649   

LigandPNGBDBM519649(US11142525, Example 50)
Affinity DataKi:  0.140nMAssay Description:HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay (MSA). The reactions were conducted in 50 μL volumes in 96-well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent