BDBM519730 US11142525, Example 131

SMILES CCN(C)c1cc2C(=O)N(Cc2c(CNC)n1)c1cccc(n1)-c1nncn1CC

InChI Key InChIKey=JWNJAIXVUUYRGR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519730   

LigandPNGBDBM519730(US11142525, Example 131)
Affinity DataKi:  0.110nMAssay Description:HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay (MSA). The reactions were conducted in 50 μL volumes in 96-well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent