BDBM519778 US11142525, Example 180::US11142525, Example 181

SMILES CCC(CC(F)(F)F)n1cnnc1-c1cccc(n1)N1Cc2c(cc(nc2CNC)C2(C)CC2)C1=O

InChI Key InChIKey=JPAHUZMLRDQURM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 519778   

LigandPNGBDBM519778(US11142525, Example 181 | US11142525, Example 180)
Affinity DataKi:  0.130nMAssay Description:HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay (MSA). The reactions were conducted in 50 μL volumes in 96-well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

LigandPNGBDBM519778(US11142525, Example 181 | US11142525, Example 180)
Affinity DataKi:  25.1nMAssay Description:HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay (MSA). The reactions were conducted in 50 μL volumes in 96-well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent