BDBM520855 5-[({6-Bromo-2-[3-ethylpiperidin-1-yl]-3-methylquinolin-4-yl}carbonyl)amino]-4-[2-(trifluoromethoxy)phenyl]pentanoic acid (Diastereomer Mixture)::US11149018, Example 139

SMILES CCC1CCCN(C1)c1nc2ccc(Br)cc2c(C(=O)NCC(CCC(O)=O)c2ccccc2OC(F)(F)F)c1C

InChI Key InChIKey=DQRZOTAIJHFPHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520855   

TargetProstaglandin F2-alpha receptor(Human)
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US Patent
LigandPNGBDBM520855(US11149018, Example 139 | 5-[({6-Bromo-2-[3-ethylp...)
Affinity DataIC50: 1.5nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent