BDBM520944 5-[({6-Bromo-2-[3-ethylpiperidin-1-yl]-3-methylquinolin-4-yl}carbonyl)amino]-4-(2,5-difluorophenyl)pentanoic acid (Diastereomer Mixture)::US11149018, Example 225::US11149018, Example 228

SMILES CC[C@H]1CCCN(C1)c1nc2ccc(Br)cc2c(C(=O)NC[C@H](CCC(O)=O)c2cc(F)ccc2F)c1C

InChI Key InChIKey=AIQKFSQLDWKWQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520944   

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520944(US11149018, Example 228 | 5-[({6-Bromo-2-[3-ethylp...)
Affinity DataIC50: 1.10nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM520944(US11149018, Example 228 | 5-[({6-Bromo-2-[3-ethylp...)
Affinity DataIC50: 3.20nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent