BDBM521518 US11149040, Example 49.0

SMILES Cc1cnc([C@H](OC(C)C)[C@H](C)S(=O)(=O)Nc2nnc3n2-c2c(F)cccc2/C=C\CC3)nc1

InChI Key InChIKey=HIRXZHBRGAQDAD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 521518   

TargetApelin receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 521518BDBM521518(US11149040, Example 49.0)
Affinity DataEC50:  98nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent