BDBM521519 US11149040, Example 50.0::US11149040, Example 51.0::US11149040, Example 52.0::US11149040, Example 53.0

SMILES Cc1cnc([C@H](OC(C)C)[C@H](C)S(=O)(=O)Nc2nnc3n2-c2c(F)cccc2/C=C\C[C@@H]3C)nc1

InChI Key InChIKey=VRDCHUVVRYRUFM-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 521519   

TargetApelin receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 521519BDBM521519(US11149040, Example 53.0 | US11149040, Example 51....)
Affinity DataEC50:  8.60nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 521519BDBM521519(US11149040, Example 53.0 | US11149040, Example 51....)
Affinity DataEC50:  12nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 521519BDBM521519(US11149040, Example 53.0 | US11149040, Example 51....)
Affinity DataEC50:  220nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 521519BDBM521519(US11149040, Example 53.0 | US11149040, Example 51....)
Affinity DataEC50: >1.25E+4nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent