BDBM523042 US11161854, Example 3.5-1::US11161854, Example 3.5-3::US11161854, Example 3.5-4::US11161854, Example 3.5-5::US11161854, Example 3.5-7

SMILES CC1C(CCN1c1cc(ncn1)-n1ncc2ccc(cc12)[C@]1(CC11CC1)C#N)C(C)(C)O

InChI Key InChIKey=QEEQAZIZVOESQO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 523042   

LigandPNGBDBM523042(US11161854, Example 3.5-1 | US11161854, Example 3....)
Affinity DataIC50: 0.600nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM523042(US11161854, Example 3.5-1 | US11161854, Example 3....)
Affinity DataIC50: 1.90nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM523042(US11161854, Example 3.5-1 | US11161854, Example 3....)
Affinity DataIC50: 5.10nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM523042(US11161854, Example 3.5-1 | US11161854, Example 3....)
Affinity DataIC50: 27.6nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM523042(US11161854, Example 3.5-1 | US11161854, Example 3....)
Affinity DataIC50: 123nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent