BDBM523043 US11161854, Example 3.5-2::US11161854, Example 3.5-6::US11161854, Example 3.5-8

SMILES CC1C(CCN1c1cc(ncn1)-n1ncc2ccc(cc12)[C@@]1(CC11CC1)C#N)C(C)(C)O

InChI Key InChIKey=QEEQAZIZVOESQO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 523043   

LigandPNGBDBM523043(US11161854, Example 3.5-2 | US11161854, Example 3....)
Affinity DataIC50: 31.6nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

LigandPNGBDBM523043(US11161854, Example 3.5-2 | US11161854, Example 3....)
Affinity DataIC50: 4.90nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

LigandPNGBDBM523043(US11161854, Example 3.5-2 | US11161854, Example 3....)
Affinity DataIC50: 1.10nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent