BDBM523058 US11161854, Example 3.8-1::US11161854, Example 3.8-2::US11161854, Example 3.8-3

SMILES C[C@H]1CN(CCN1C1CCOC1)c1cc(ncn1)-n1ncc2ccc(cc12)[C@]1(CC11CC1)C#N

InChI Key InChIKey=FQCGGCCNGKFEMR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 523058   

LigandPNGBDBM523058(US11161854, Example 3.8-1 | US11161854, Example 3....)
Affinity DataIC50: 0.800nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM523058(US11161854, Example 3.8-1 | US11161854, Example 3....)
Affinity DataIC50: 1.30nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM523058(US11161854, Example 3.8-1 | US11161854, Example 3....)
Affinity DataIC50: 1.60nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent