BDBM523081 US11161854, Example 4.9-1::US11161854, Example 4.9-2

SMILES OCC1CN(CCO1)c1cc(ncn1)-n1ncc2ccc(cc12)[C@@]1(CC11CC1)C#N

InChI Key InChIKey=WXHQENLWWKVPPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523081   

LigandPNGBDBM523081(US11161854, Example 4.9-1 | US11161854, Example 4....)
Affinity DataIC50: 0.600nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

LigandPNGBDBM523081(US11161854, Example 4.9-1 | US11161854, Example 4....)
Affinity DataIC50: 0.600nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent