BDBM523085 US11161854, Example 4.11-2

SMILES COCc1nc(cc(n1)-n1ncc2ccc(cc12)[C@@]1(CC11CC1)C#N)N1CCN(C2COC2)[C@@H](C)C1

InChI Key InChIKey=YTMRWPZYQKYUQW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523085   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S](Human)
Merck Sharp & Dohme

US Patent

LigandBDBM523085(US11161854, Example 4.11-2)Copy SMILESCopy InChI

Affinity DataIC50: 0.700nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/20/2022
Entry Details
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