BDBM523115 US11161854, Example 5.6-1::US11161854, Example 5.6-2

SMILES Cc1nc(cc(n1)-n1ncc2cc(F)c(cc12)C1(CC11CC1)C#N)N1CC2(CC1C2)C(C)(C)O

InChI Key InChIKey=GNTXGDSZRJKWCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523115   

LigandPNGBDBM523115(US11161854, Example 5.6-1 | US11161854, Example 5....)
Affinity DataIC50: 1.30nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM523115(US11161854, Example 5.6-1 | US11161854, Example 5....)
Affinity DataIC50: 20.9nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent