BDBM523442 US11136296, Example 173::US11136296, Example 222::US11136296, Example 250

SMILES Cc1c(nc2ccc(Br)cc2c1C(=O)NC[C@H](CCC(O)=O)c1c(F)ccc(F)c1Cl)-c1ccccc1

InChI Key InChIKey=YZDHMNSJTDELSQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 523442   

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523442(US11136296, Example 173 | US11136296, Example 250 ...)
Affinity DataIC50: 0.960nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523442(US11136296, Example 173 | US11136296, Example 250 ...)
Affinity DataIC50: 1.10nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM523442(US11136296, Example 173 | US11136296, Example 250 ...)
Affinity DataIC50: 17nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent