BDBM523799 US11136312, Compound AH.2.199

SMILES C(Cc1c[nH]cn1)Cn1c(Cc2ccccc2)nnc1SCc1ccccc1

InChI Key InChIKey=UUHUEWYWPKZLBJ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 523799   

TargetSomatostatin receptor type 4(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523799BDBM523799(US11136312, Compound AH.2.199)
Affinity DataKi:  80.8nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetSomatostatin receptor type 4(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523799BDBM523799(US11136312, Compound AH.2.199)
Affinity DataKi:  81nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSomatostatin receptor type 3(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523799BDBM523799(US11136312, Compound AH.2.199)
Affinity DataEC50:  144nMAssay Description:Measurement of forskolin stimulated inhibition of cAMP was performed via time-resolved fluorescence resonance energy transfer (TR-FRET) LANCE assay (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523799BDBM523799(US11136312, Compound AH.2.199)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523799BDBM523799(US11136312, Compound AH.2.199)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed