BDBM523985 US11136329, Compound 94::isopropyl 2-(4-((7-(2- isopropyl-3- methylbutyl)-7H- pyrrolo[2,3-d]pyrimidin- 2-yl)amino)-1H-pyrazol- 1-yl)acetate

SMILES CC(C)OC(=O)Cn1cc(Nc2ncc3ccn(CC(C(C)C)C(C)C)c3n2)cn1

InChI Key InChIKey=PQBHSOQKOJYJIX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 523985   

TargetTyrosine-protein kinase JAK2(Human)
Vimalan Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 523985BDBM523985(US11136329, Compound 94 | isopropyl 2-(4-((7-(2- i...)
Affinity DataIC50: 100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Vimalan Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 523985BDBM523985(US11136329, Compound 94 | isopropyl 2-(4-((7-(2- i...)
Affinity DataIC50: 100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Vimalan Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 523985BDBM523985(US11136329, Compound 94 | isopropyl 2-(4-((7-(2- i...)
Affinity DataIC50: 100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Vimalan Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 523985BDBM523985(US11136329, Compound 94 | isopropyl 2-(4-((7-(2- i...)
Affinity DataIC50: 100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent