BDBM524857 US11168093, Example 127a::US11168093, Example 127b::US11168093, Example 127c::US11168093, Example 127d

SMILES CC1C(CCCN1C)c1cc2c(Nc3c(F)cc4scnc4c3F)c(F)cnc2s1

InChI Key InChIKey=ZZNFNTQEAZRAIX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524857   

LigandPNGBDBM524857(US11168093, Example 127a | US11168093, Example 127...)
Affinity DataIC50: 10nMAssay Description:All data was collected using a standard TR-FRET screening assay: LanthaScreen Tracer 199 at 50 nM, Eu-anti-His Antibody at 2 nM, 5 nM RIPK2 enzyme, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

LigandPNGBDBM524857(US11168093, Example 127a | US11168093, Example 127...)
Affinity DataIC50: 10nMAssay Description:All data was collected using a standard TR-FRET screening assay: LanthaScreen Tracer 199 at 50 nM, Eu-anti-His Antibody at 2 nM, 5 nM RIPK2 enzyme, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

LigandPNGBDBM524857(US11168093, Example 127a | US11168093, Example 127...)
Affinity DataIC50: 15nMAssay Description:All data was collected using a standard TR-FRET screening assay: LanthaScreen Tracer 199 at 50 nM, Eu-anti-His Antibody at 2 nM, 5 nM RIPK2 enzyme, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

LigandPNGBDBM524857(US11168093, Example 127a | US11168093, Example 127...)
Affinity DataIC50: 35nMAssay Description:All data was collected using a standard TR-FRET screening assay: LanthaScreen Tracer 199 at 50 nM, Eu-anti-His Antibody at 2 nM, 5 nM RIPK2 enzyme, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent