BDBM525417 US11174232, Compound 94

SMILES O=C(/C=C/CN1CCCC1)Nc1ccc(-c2cccc(C3(C(=O)Nc4cc(C5CC5)[nH]n4)CC3)c2)cn1

InChI Key InChIKey=KAPLPYXIOOIIAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 525417   

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 525417BDBM525417(US11174232, Compound 94)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit CDK7 kinase activity was tested in a TR-FRET assay using 5 nM of CDK7/CycH/MNAT1 obtained from Invitrogen, USA. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent