BDBM525844 US11174254, Compound G-5
SMILES COCCOc1ccc(Nc2nc(Nc3cccc(NC(=O)C=C)c3)c(F)c3c2C(=O)NC3(C)C)cc1
InChI Key InChIKey=ILQZUHJBPQMRAN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 525844
Affinity DataIC50: 156nMAssay Description:The compound was predissolved in 100% DMSO.10 mM drug stock solution was obtained by dissolution at room temperature and then gradiently diluted with...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Yangtze River Pharmaceutical Group
US Patent
Yangtze River Pharmaceutical Group
US Patent
Affinity DataIC50: 7.85E+3nMAssay Description:The inhibitory activity of compounds to be tested on wild-type EGFR kinase (Invitrogen, PV3872) was measured by z-lyte methods.The working concentrat...More data for this Ligand-Target Pair