BDBM527666 US11186589, Compound 31

SMILES CN1CCc2ccc(Nc3nccc(n3)-c3cc4c(NC[C@]4(C)CO)c(c3)C#N)cc2C1

InChI Key InChIKey=JQEVFUMHNRRKQM-RUZDIDTESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527666   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM527666(US11186589, Compound 31)
Affinity DataIC50:  1.40nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (αscreen) format (Perkin Elmer). All compounds tested were dissolv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent