BDBM528725 US11198681, Compound I-52

SMILES CCn1c(nc2cc(cc(OC)c12)C(=O)N1CCC[C@@H](N)C1)-c1cn(CC2CC2)c(n1)-c1ccccc1

InChI Key InChIKey=FTNTXJHJFLVKPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 528725   

TargetProtein-arginine deiminase type-4(Human)
Padlock Therapeutics

US Patent
LigandPNGBDBM528725(US11198681, Compound I-52)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetProtein-arginine deiminase type-4(Mouse)
Padlock Therapeutics

US Patent
LigandPNGBDBM528725(US11198681, Compound I-52)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetProtein-arginine deiminase type-4(Human)
Padlock Therapeutics

US Patent
LigandPNGBDBM528725(US11198681, Compound I-52)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent