BDBM529373 US11198699, Compound 3

SMILES Cc1ncnc2n(ccc12)[C@@H]1C[C@](C)(CCc2cc(F)c3cc(Cl)c(N)nc3c2)[C@H]2OC(C)(C)O[C@@H]12

InChI Key InChIKey=BAEGBPBNFVFGDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 529373   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aligos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 529373BDBM529373(US11198699, Compound 3)
Affinity DataIC50: 100nMAssay Description:Assay 2: Compounds were tested for inhibition of methyltransferase activity in 384-well plate assay format using mass spectrometry technology. In thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2022
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aligos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 529373BDBM529373(US11198699, Compound 3)
Affinity DataIC50: 100nMAssay Description:Assay 1: Compounds were tested for inhibition of methyltransferase activity in a radioisotope filter binding assay, similar to previously described i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2022
Entry Details
US Patent