BDBM529377 US11198699, Compound 7

SMILES Nc1ncnc2n(ccc12)[C@@H]1[C@H]2C[C@@]2([C@H](O)c2ccc(Cl)c(Cl)c2)[C@@H](O)[C@H]1O

InChI Key InChIKey=NXMGAWHQVFJJAK-XGNHOHPRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 529377   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aligos Therapeutics

US Patent
LigandPNGBDBM529377(US11198699, Compound 7)
Affinity DataIC50:  50nMAssay Description:Assay 2: Compounds were tested for inhibition of methyltransferase activity in 384-well plate assay format using mass spectrometry technology. In thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aligos Therapeutics

US Patent
LigandPNGBDBM529377(US11198699, Compound 7)
Affinity DataIC50: <1nMAssay Description:Assay 1: Compounds were tested for inhibition of methyltransferase activity in a radioisotope filter binding assay, similar to previously described i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent