BDBM530044 (3R)-4-(1-(5- fluoro-4- methoxypyrimidin- 2-yl)piperidine-4- carbonyl)-3-methyl- 2,3,4,5- tetrahydropyrido[3, 4-f][1,4]oxazepine- 9-carbonitrile::US11203600, Example 120

SMILES COc1nc(ncc1F)N1CCC(CC1)C(=O)N1Cc2cncc(C#N)c2OC[C@H]1C

InChI Key InChIKey=PMLRDCCRDRFTNR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530044   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM530044((3R)-4-(1-(5- fluoro-4- methoxypyrimidin- 2-yl)pip...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent