BDBM530056 (1-(4-(2,2- difluoroethoxy)-5- fluoropyrimidin-2- yl)-4- methoxypiperidin- 4-yl)(9-fluoro-2,3- dihydropyrido[3,4- f][1,4]oxazepin- 4(5H)- yl)methanone::US11203600, Example 132

SMILES COC1(CCN(CC1)c1ncc(F)c(OCC(F)F)n1)C(=O)N1CCOc2c(C1)cncc2C#N

InChI Key InChIKey=IOEKDZMPZQZBCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530056   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM530056((1-(4-(2,2- difluoroethoxy)-5- fluoropyrimidin-2- ...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent