BDBM530059 (9-fluoro-3,5- dihydro-2H- pyrido[3,4- f][1,4]oxazepin-4- yl)-(4-methoxy-1- pyrimidin-2-yl-4- piperidyl)methanone::US11203600, Example 135

SMILES COC1(CCN(CC1)c1ncccn1)C(=O)N1CCOc2c(F)cncc2C1

InChI Key InChIKey=WTOIKZDQYDJWPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530059   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM530059((9-fluoro-3,5- dihydro-2H- pyrido[3,4- f][1,4]oxaz...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent