BDBM530069 4-(2,2,3- trimethylbutanoyl)- 3,5-dihydro-2H- pyrido[3,4- f][1,4]oxazepine-9- carbonitrile::US11203600, Example 145

SMILES CC(C)C(C)(C)C(=O)N1CCOc2c(C1)cncc2C#N

InChI Key InChIKey=VLZZXWZPAWFNFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530069   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM530069(4-(2,2,3- trimethylbutanoyl)- 3,5-dihydro-2H- pyri...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent