BDBM530267 WO2022064009, Compound 44

SMILES C[C@@H]1Cc2cnc(NC3CCS(=O)(=O)CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1

InChI Key InChIKey=ZLAMRJYPPCFJBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530267   

LigandChemical structure of BindingDB Monomer ID 530267BDBM530267(WO2022064009, Compound 44)
Affinity DataIC50: 9.12nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

LigandChemical structure of BindingDB Monomer ID 530267BDBM530267(WO2022064009, Compound 44)
Affinity DataIC50: 20nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009