BDBM530351 WO2022064009, Compound 105

SMILES CO[C@H]1CC[C@H](Nc2ncc3c(n2)CN(C(=O)[C@@H]2CCN(C)C[C@H]2c2ccnc(C)c2)[C@H](C)C3)CC1

InChI Key InChIKey=VXWBPLNIVFITGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530351   

LigandChemical structure of BindingDB Monomer ID 530351BDBM530351(WO2022064009, Compound 105)
Affinity DataIC50: 9.77nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

LigandChemical structure of BindingDB Monomer ID 530351BDBM530351(WO2022064009, Compound 105)
Affinity DataIC50: 10nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009